Barb Mucha was born in Parma Heights, Ohio in 1961.

During her career at Michigan State University, she won two individual titles, including the Ohio State Invitational. In 1984, Mucha received All-American honors.

She turned professional in 1985 and quickly found success on the LPGA Futures Tour, where she posted six victories.

In 1987, she qualified for the LPGA Tour, where she'd go on to win five times and earn over $2.4 million.

Her first LPGA Tour victory came at the 1990 Boston Five Classic, in a playoff. She also was victorious at the 1992 Oldsmobile Classic, the 1994 State Farm Rail Classic, the 1996 Chick-Fil-A Charity Championship, and the 1998 Sara Lee Classic. The latter of which came in a four-way playoff, one that included Nancy Lopez.

Of the 321 LPGA-sanctioned events in which she competed in, Barb posted 115 top-10 finishes.

After her playing career, she began teaching at Grand Cypress Resort in Orlando, Florida. She also has served as a spokesperson with the Ohio Girls Golf Foundation.